Cryogenic High Energy Vibratory Ball Mill Ultra Low Temperature Laboratory Tissue Lyzer Grinder

Vibration Ball Mill

Cryogenic High Energy Vibratory Ball Mill Ultra Low Temperature Laboratory Tissue Lyzer Grinder

Item Number: PP-VB30

Final Particle Size: ~ 5 µm Minimum Temperature Detection: -200°C Vibration Frequency Range: 180 – 1800 r/min
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Product Overview

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This high-performance cryogenic vibratory ball mill is engineered to deliver rapid, efficient, and reproducible sample reduction for challenging laboratory and industrial research applications. By combining intense mechanical impact and frictional forces with continuous liquid nitrogen cooling, the equipment effectively embrittles tough, elastic, or temperature-sensitive substances that cannot be processed at ambient temperatures. The system achieves exceptional final particle fineness down to approximately 5 µm, providing an ideal preparation solution for downstream spectroscopic, chromatographic, and molecular analysis.

Designed for maximum versatility, the unit handles a broad spectrum of sample matrices including hard ceramics, medium-hard minerals, brittle crystals, soft biological tissue, fibrous plant material, and elastic polymers. Operating across dry, wet, and sub-zero cryogenic milling regimes, this system integrates dual heat-exchange workstations capable of running simultaneous grinding jars or specialized multi-tube cell disruption adapters. Target industries span materials science, metallurgy, polymer engineering, environmental testing, pharmaceutical formulation, molecular biology, and forensic research.

Built to withstand rigorous continuous and intermittent operating schedules, the equipment features a heavy-duty industrial drive mechanism, IP63 protection against dust and fluid splash, and an integrated soundproofing enclosure. Digital microprocessor controls provide real-time temperature tracking down to -200°C, precise frequency regulation, and power failure memory, ensuring operational safety, complete batch-to-batch consistency, and long-term reliability in high-throughput sample preparation environments.

Key Features

  • High-Energy Reciprocating Motion: Driven by an advanced horizontal arc reciprocal movement operating between 180 and 1800 r/min, generating extreme impact and shear stress for rapid pulverization down to ~5 µm.
  • Integrated Ultra-Low Temperature System: Features a built-in liquid nitrogen heat exchanger with real-time digital temperature sensing capable of reaching -200°C, preventing thermal degradation and enabling brittle fracture of elastic polymers and biological samples.
  • Dual Heat Exchange Workstations: Equipped with two independent grinding stations configured for heat-exchange cooling, enabling high-throughput parallel processing of two large jars or multiple micro-vials simultaneously.
  • Multi-Mode Grinding Capability: Performs dry grinding, wet slurry milling, and ultra-low temperature cryogenic processing to accommodate hard, brittle, fibrous, viscous, soft, and elastic material characteristics.
  • Precision Digital Control & Memory: Microprocessor controller provides full speed regulation, process timing, continuous or intermittent operation modes, protocol data storage, and automatic power failure memory for absolute experiment repeatability.
  • High-Efficiency Cell Disruption: Supports dedicated multi-tube adapters for high-throughput cell disruption and tissue homogenization, accommodating 10x0.2ml, 5x2ml, or 3x5ml sample vessel arrays.
  • Comprehensive Material Compatibility: Offers grinding jars and grinding balls in tungsten carbide, zirconia, stainless steel, MC nylon, PTFE, and agate to eliminate sample contamination and material cross-reactivity.
  • Robust Safety and Noise Isolation: Integrated soundproofing cabinet significantly dampens operational noise, while an open-cover auto-shutoff safety switch and electrical overload protection protect lab personnel and internal components.
  • Industrial Protection Housing: IP63-rated enclosure protects sensitive internal electronics and mechanical drives against ambient dust, sample dust, and cryogenic moisture condensation.

Applications

Application Description Key Benefit
Polymer & Rubber Recycling Research Cryogenic pulverization of ductile plastics, elastomers, tire rubber, and synthetic resins at sub-zero temperatures. Embrittles elastic polymers to prevent melting or thermal degradation during high-energy milling.
Biological Cell Disruption & Genomics Rapid disruption of plant tissues, animal cells, bacteria, and yeast in multi-vial adapter blocks using liquid nitrogen cooling. Preserves heat-sensitive RNA, DNA, and proteins while achieving thorough cell wall breakdown.
Pharmaceutical Active Ingredient Milling Fine wet or dry pulverization of thermolabile active pharmaceutical ingredients (APIs) and excipients under controlled conditions. Prevents phase transformation and thermal decomposition of sensitive active chemical compounds.
Advanced Ceramics & Metallurgy High-energy impact comminution of hard ceramic oxides, nitrides, carbide powders, and alloy bits down to ~5 µm. Delivers rapid particle size reduction without introducing unwanted metallic contaminants when using matched jar media.
Environmental & Agricultural Testing Homogenization of dry soil, compost, sewage sludge, wood fibers, and agricultural plant samples for trace element analysis. Ensures high analytical representativeness across non-homogeneous, fibrous, and organic sample matrices.
Forensic Science & Toxicology Pulverization of tough human or animal tissues, bones, hair, and teeth for forensic chemical extraction. Complete sample reduction without structural thermal damage, enabling high-yield analyte recovery.

Technical Specifications

Parameter Specification
Model Identifier PP-VB30
Equipment Name Cryogenic High-Energy Vibratory Ball Mill
Processing Principle Impact Force and Friction Force
Applicable Sample Characteristics Hard, Medium-Hard, Brittle, Dry, Viscous, Fibrous, Soft, Elastic
Processing Types Comminution / Pulverization, Mixing, Homogenization, Cryogenic Grinding, Cell Disruption
Recommended Maximum Feed Size < 8 mm
Final Particle Size Range ~ 5 µm
Grinding Modes Dry Grinding, Wet Grinding, Cryogenic Grinding
Heat Exchange Platforms / Workstations 2 Workstations
Motion Type Horizontal Arc Reciprocal Motion
Vibration Frequency Range 180 – 1800 r/min
Main Control Functions Ultra-Low Temperature Detection, Continuous Operation, Intermittent Operation, Process Timing, Speed Regulation, Data Storage, Power Failure Memory, Overload Protection
Additional Features Soundproofing Enclosure, Open-Cover Protective Shutoff
Control Mode Digital Microprocessor Control
Built-in Heat Exchange System Yes (Integrated Heat Exchanger Included)
Cooling Medium Liquid Nitrogen (LN2)
Liquid Nitrogen Tank Type Self-Pressurized Type
Liquid Nitrogen Tank Options 30 L / 50 L Optional
Minimum Temperature Detection -200°C
Cell Disruption Adapter Capacities 10 × 0.2 ml | 5 × 2 ml | 3 × 5 ml
Grinding Jar Material Options Tungsten Carbide, Zirconia, Stainless Steel, MC Nylon, PTFE, etc.
Grinding Jar Capacities 2 ml, 5 ml, 10 ml, 30 ml, 50 ml
Grinding Jar Sealing Method High-Performance Sealing Ring + Thread Tightening
Grinding Jar Locking Method Sealing Ring + Thread Locking
Grinding Ball Diameter Options 1 – 25 mm Optional
Grinding Ball Material Options Tungsten Carbide, Zirconia, Agate, Stainless Steel
Electrical Specifications 100-120V / 200-240V AC, 50-60 Hz, 150 W
Power Plug Options National Standard, European Standard, US Standard, UK Standard, etc.
Protection Rating IP63
Standard Certifications CE Certified
Net Weight 48 kg
Dimensions (L × W × H) 470 × 360 × 250 mm

Why Choose This Product

  • Uncompromising Low-Temperature Milling: Purpose-built for cryogenic operation down to -200°C, ensuring rapid embrittlement and effortless grinding of elastic polymers, soft biological samples, and heat-sensitive pharmaceuticals.
  • Heavy-Duty Precision Engineering: Constructed with heavy-duty internal drives, an IP63 dust- and splash-proof housing, and robust safety interlocks to guarantee long-term operational consistency under demanding continuous laboratory usage.
  • Extensive Material Flexibility: Supports a wide array of jar volumes (2 ml to 50 ml) and high-purity, wear-resistant media materials (tungsten carbide, zirconia, agate, PTFE) to prevent cross-contamination and satisfy strict analytical requirements.
  • Automated Digital Reproducibility: Features full digital frequency control (180-1800 r/min), program timing, multi-step parameter storage, and power failure memory, enabling seamless protocol standardization across laboratory teams.
  • Comprehensive Application Support: Backed by our team of experienced sample preparation specialists offering expert technical consultation, customized adapter options, and responsive global after-sales support.

Contact our sales engineering team today to request a formal quotation, discuss custom adapter options, or evaluate sample test grinding for your laboratory requirements.

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