High Throughput Biological Homogenizer and Cell Disrupter for DNA RNA and Protein Extraction

Planetary Ball Mills

High Throughput Biological Homogenizer and Cell Disrupter for DNA RNA and Protein Extraction

Item Number: PP-BM05

Processing Capacity: Up to 24 x 2ml or 12 x 5ml Centrifugal Speed: Max. 2000-6000 rpm Temperature Control Range: -40°C to 37°C (variant dependent)
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Product Overview

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This high-speed biological homogenization system is engineered to meet the rigorous demands of modern molecular biology and material science laboratories. Designed specifically for the rapid disruption of diverse biological samples, the equipment utilizes a combination of high-frequency 3D vibration and intense friction to release DNA, RNA, and proteins with exceptional efficiency. By automating the lysis process, this unit ensures that samples are processed with maximum consistency, facilitating high-quality downstream extraction and purification protocols for research and diagnostic applications.

Targeting industries ranging from agriculture and environmental science to clinical pathology and forensics, the system offers a versatile platform for processing complex matrices. Whether handling soft animal tissues, fibrous plant materials, or resistant fungal spores, the equipment maintains the integrity of delicate biomolecules. Its robust construction and powerful motor allow for high-throughput processing, accommodating dozens of samples simultaneously without compromising on the quality of the homogenate, making it an essential tool for high-volume genomic and proteomic workflows.

Reliability is at the core of this unit's design, ensuring stable performance even under intensive laboratory conditions. The integration of advanced cooling systems in specialized variants protects thermosensitive samples from degradation during high-energy grinding cycles. With a focus on user safety and process repeatability, this system provides a sealed environment that prevents cross-contamination and environmental exposure. Procurement teams can rely on this equipment as a long-term investment that enhances laboratory productivity while maintaining the highest standards of sample preparation precision.

Key Features

  • Integrated 3D Vibratory Technology: The equipment employs a sophisticated three-dimensional high-speed motion profile that combines shearing and abrading forces. This multi-directional energy transfer ensures that grinding balls impact samples from all angles, achieving complete cell wall and membrane lysis in significantly less time than traditional vortexing or manual methods.
  • Precision Temperature Regulation: For temperature-sensitive biological applications, the refrigerated versions of this system utilize high-efficiency compressor cooling. This allows for precise thermal management, with customizable ranges available down to -40°C, ensuring that the heat generated during the friction-heavy grinding process does not denature proteins or degrade nucleic acids.
  • High-Throughput Processing: The system is engineered to handle substantial workloads, capable of processing up to 48 samples in a single batch when configured with high-density adapters. It supports standard 2ml and 5ml centrifuge or cryogenic tubes, allowing laboratories to scale their operations without needing proprietary consumables.
  • Intuitive Touchscreen Interface: A 7-inch high-resolution color touchscreen provides an easy-to-use control hub for the operator. Users can monitor real-time parameters and navigate settings with minimal training, ensuring that the system can be deployed quickly in multi-user laboratory environments.
  • Programmable SOP Management: To ensure experimental repeatability, the unit features an extensive memory for up to 99 Standard Operating Procedures (SOPs). Parameters such as grinding time, cycle frequency, interval pauses, and centrifugal speed can be saved and locked, eliminating manual entry errors and ensuring consistent results across different shifts.
  • Integrated Centrifugal Separation: Uniquely, this equipment integrates 3D vibratory pulverizing with centrifugal separation capabilities. This dual-functionality saves significant operation time by allowing for the immediate sedimentation of debris following the lysis step, reducing the need for sample transfer and minimizing the risk of contamination.
  • Variable Speed Control for Genomic Integrity: The system offers a wide range of vibration and centrifugal speeds. Low-speed crushing modes are specifically optimized for genome preparation where preserving the length of DNA fragments is critical, while high-speed modes provide the energy required for difficult-to-lyse samples like bone or seeds.
  • Contamination-Free Environment: By utilizing disposable tubes and a fully enclosed grinding chamber, the system eliminates the possibility of sample-to-sample cross-contamination. This is particularly vital for PCR-based applications and forensic analysis where even trace amounts of foreign DNA can compromise results.
  • Industrial-Grade Build Quality: Constructed with premium materials and a high-torque motor, the unit is designed for durability. The internal components are resistant to the vibrations inherent in high-speed grinding, ensuring a long service life and minimal maintenance requirements for busy industrial and research facilities.

Applications

Application Description Key Benefit
Agricultural Genomics Disruption of hardy seeds, stems, and leaves for transgenic research and crop improvement. High-energy grinding breaks through tough cellulose walls efficiently.
Clinical Diagnostics Homogenization of human or animal biopsy tissues, organs, and bone for pathology. Consistent lysis ensures high yields of diagnostic-grade DNA and RNA.
Microbiology Lysis of yeast, fungi, and bacterial spores for metabolite and protein analysis. 3D motion ensures even the most resistant cell walls are breached.
Environmental Science Processing of soil, sediment, and water filter samples for metagenomic studies. Integrated centrifugal separation helps isolate microbial DNA from debris.
Forensic Analysis Extraction of biological material from evidence such as hair, teeth, or dried stains. Sealed system prevents external DNA contamination and ensures chain of custody.
Food Safety Testing Preparation of food samples for the detection of pathogens or GMO ingredients. Rapid processing allows for high-volume screening in quality control labs.
Pharmaceutical R&D Preparation of tissues for drug metabolism and pharmacokinetics (DMPK) studies. Precise temperature control maintains the activity of metabolic enzymes.

Technical Specifications

Parameter PP-BM05 (Standard) PP-BM05R (Refrigerated) PP-BM05R40 (Extended Low Temp)
Process Capacity 24 x 2ml / 12 x 5ml 24 x 2ml / 12 x 5ml 24 x 2ml / 12 x 5ml
Vibration Linear Speed 2.0 - 6.5 m/s 2.0 - 6.5 m/s 2.0 - 6.5 m/s
Centrifugal Speed Max. 2000 - 6000 rpm Max. 2000 - 6000 rpm Max. 2000 - 6000 rpm
3D Grinding Speed Max. 2000 - 4000 rpm Max. 2000 - 4000 rpm Max. 2000 - 4000 rpm
Temperature Control N/A (Ambient) 4°C - 37°C -40°C - 20°C
Storable SOPs 99 Programs 99 Programs 99 Programs
Cycling Times 1 - 99 times 1 - 99 times 1 - 99 times
Max Grinding Time 99 min 59 sec 99 min 59 sec 99 min 59 sec
Rated Power 640 W 850 W 1100 W
Power Supply 220 V, 50/60 Hz 220 V, 50 Hz 220 V, 50 Hz
Display 7" Color Touch Screen 7" Color Touch Screen 7" Color Touch Screen

Why Choose This Product

  • Superior Engineering Precision: The unique combination of 3D high-speed vibratory motion and integrated centrifugal separation optimizes the entire sample preparation workflow, reducing manual labor and processing time by up to 60% compared to traditional methods.
  • Unmatched Thermal Stability: Our advanced compressor-based refrigeration systems are specifically tuned for biological preservation, offering temperature stability that is critical for maintaining the liveness of samples and preventing the degradation of sensitive RNA and protein markers.
  • Professional SOP Control: The ability to store and lock 99 distinct programs ensures that your laboratory remains compliant with strict quality management systems (QMS), providing verifiable and repeatable results every time, regardless of the operator.
  • Robust Industrial Design: Built to withstand the high-energy forces required for cell disruption, this equipment utilizes premium materials that resist wear and tear, ensuring a low total cost of ownership and minimal downtime in high-volume settings.
  • Comprehensive Support and Customization: Beyond the standard configurations, we offer specialized adapters and custom temperature ranges (such as the -40°C variant) to meet the unique challenges of your specific research or industrial process.

For laboratories requiring the highest standards of efficiency and sample integrity, this system represents the pinnacle of homogenization technology. Contact our technical team today for a detailed quote or to discuss a customized solution for your specific application needs.

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